Antibody Engineering

ABOUT CHAI DISCOVERY

Chai is a research lab working on generative models for molecular design. We are building AI infrastructure to engineer new medicines with speed and precision. The world’s largest pharmaceutical companies—including Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, and Novartis https://www.chaidiscovery.com/news/novartis-partnership—have started adopting our platform across their organizations.

Our mission is to unlock progress towards better cures and better science, and we see countless interesting problems on the road ahead. We are known for talent density, rigorous research and pace of execution.

Our founders have been at the forefront of this field from the beginning. We are backed by Sequoia, Index, Thrive, General Catalyst, Dimension, OpenAI and others.

ABOUT THE ROLE

We are looking for exceptional antibody engineers and computational protein designers to help us evaluate, expand and apply the capabilities of our de novo antibody design models. You'll join an elite team of biologists, computational scientists and AI researchers.

Scientists at Chai are power users and test pilots of our AI platform. We probe the design space for novel targets and formats, validate in silico solutions for function in the lab, and distill empirical rules from the results. We execute experimental programs at scale that guide, train and evaluate next generation models, working closely with our AI research team. We partner with scientists from the world's leading pharma companies to push their discovery programs into new territory. I think you could be a good fit.

This is an opportunity to push the boundaries of applied biology and artificial intelligence. You'll get exposed to a wide array of scientific problems and research methods, far beyond what one encounters working on a si...