Biochemist II - GMP Recombinant Protein Manufacturing
Job TitleBiochemist II - GMP Recombinant Protein ManufacturingLocation(s)San Diego - BioLegendAbout UsRevvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world’s greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our team of 11,000+ colleagues from around the globe are vital to our success and the reason we’re able to push boundaries in pursuit of better human health. Find your future at Revvity Job SummaryThis GMP recombinant protein Biochemist at BioLegend will primarily be responsible for performing protein purification, conjugation, formulation, and quality control for GMP product release. This position will assist in GMP protein manufacturing for GMP products. The position plays an important part in the success of the robust GMP recombinant protein product manufacturing and will actively support team members in managing raw material, inventory, and batch records through efforts collaborating with other departments such as manufacturing, quality assurance, and quality control teams. The Biochemist will perform purifying recombinant proteins using various preparative chromatography methods and separation using methods such as IMAC, size exclusion, and ion exchange, conjugation and formulate the recombinant proteins according to standard operating procedures compliant with ISO and GMP regulation. This position will also support a variety of cross-function manufacturing tasks including work order processing and closure of pilot lots related to product release or validation. His/her role also assists in activities for technical support, document control, validation, training, nonconformance, and CAPA systems. Essential FunctionsReasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.Following standard procedures to conduct recombinant protein or antibody purification using affinity matrix such as IMAC and Protein A Sepharose. Following standard procedures to conduct protein conjugation and polishing using various types of chromatography and AKTA FPLC. Conduct the in-process quality testing such as purity analysis, endotoxin testing for the in-house made or customized bulk material of finished goods. Support internal safety and regulatory compliance audits Support equipment operation training and validation activities for new process and equipment validationProvide benchwork support for product releasing or troubleshooting of complicated manufacturing problems in recombinant protein production to ensure sustainable manufacturing design Support reviewing...