Principal Software Engineer, Neuroscience Platforms

ABOUT THE ROLE

At Astera Neuro, we are deciphering how activity across billions of neurons becomes thought, perception, and the conscious experience of the world and ourselves. Doing that requires building cutting-edge tools and infrastructure to interface with, record, and control neural activity at an unprecedented scale.

We are hiring a Principal Software Engineer to lead the computational infrastructure that the next generation of large-scale neuroscience research will depend on. Working closely with scientists and hardware engineers, you will span the full stack of our research systems, including instrument control, data acquisition, and analysis, translating open-ended experimental goals into reliable software. The problems are latency-sensitive, multi-modal, and deeply interdisciplinary. You do not need a background in neuroscience to apply; we are looking for an exceptional, pragmatic engineer who enjoys solving hard, interesting problems and picks up the science as they go.

As a principal engineer, you will define the technical roadmap across systems, mentor other engineers, and shape how neuroscience and engineering work together at Astera.

WHAT YOU WILL BUILD

- Stimulus presentation and acquisition systems, including VR environments built in Unity, Unreal, or comparable frameworks, that synchronize peripheral streams (eye tracking, displays, haptics) with high-throughput neural recording hardware to millisecond precision.

- High-throughput pipelines to ingest, process, and store massive, multi-modal neural datasets (electrophysiology, calcium imaging, behavior), with versioned data formats, automated QC, and clear metadata standards.

- Dashboards, user interfaces, and experiment-design tools that let scientists interact with complex data and run experiments seamlessly.

- Cloud-based storage, processing and sharing infrastructure that supports distributed teams and large-scale datasets.

WHAT WE ARE LOOKING FOR

- Exceptional software...