Calyx

Scientist I, Imaging and Pharmacology

US MA NeedhamFull time$65,305 - $121,287 / yearPosted 3 days ago
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What can we offer you?Apart from job satisfaction, we can offer you:HEALTHMedical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)YOURSELFPaid time off policy including holidays and sick timeInternal growth and development programs & trainingsWEALTH401(k) program, life & accident insurance and disability insuranceWe are seeking a motivated and skilled Scientist I to support our invivo imaging studies using small animal models. This role is central to our preclinical research team and involves hands-on work with nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI). The successful candidate will play a key role in project leadership, with the opportunity to oversee staff and lab spaces. They will also provide technical support across a range of in vivo disease models, perform dosing and surgical procedures, and contribute to team leadership by mentoring junior staff.This position offers an exciting opportunity to evolve into a strategic leadership role within a fast-paced, collaborative research environment. Whether leading a small team or contributing as a senior individual contributor, you'll have the autonomy to drive research excellence and help shape the future of preclinical imaging studies.Key ResponsibilitiesTeam Leadership & Staff DevelopmentLead or support day-to-day activities within the invivo team, ensuring alignment with project timelines and goals.May oversee and develop junior staff (2-4 members) provide training and technical guidance as needed.Contribute to the management and optimization of laboratory space, including equipment and supply maintenance.Develop, write and enforce laboratory-specific standard operating procedures (SOP’s)Evaluate study protocols and collaborate with Discovery Research teams during protocol development.Liaise with IACUC and internal stakeholders to ensure compliance with animal use protocols (AUP’s)Lead onboarding and integration of new team members.Study Support & ExecutionParticipate in protocol development and review with Discovery Research and cross-functional teams.Assist in coordinating study scheduling and establish timelines for protocol execution.Execute a wide range of study types including:Efficacy, biodistribution, pharmacokinetics, toxicokinetic, and xenograft models.Perform dosing and surgical procedures such as:IV, IP, SC, IM, PO administrationsPerfusion, tissue resection, microdissectionBiological sampling (blood, CSF, organs)Survival surgery and CNS administration (preferred but not required)Assist in image acquisition (PET, SPECT, CT, MRI) and related procedures.Handle radioactive and BSL2 materials, including sample processing, gamma counting, and proper waste disposal.Ensure strict adherence to laboratory SOPs and regulatory guidelines (IACUC, radiation safety, lab safety).Ensure accurate data collection, analysis and reporting.Maintain complete and clear laboratory records.Moni...