Scientist, Immunoassay Development
Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.Summary: Vaxcyte is seeking an accomplished Scientist, Immunoassay Development to join the CMC Immunoassay group. This role will provide scientific and strategic leadership for the development, qualification, characterization, governance, and lifecycle management of critical reagents and reference materials that support immunoassays across Vaxcyte's vaccine pipeline. This is an onsite, laboratory-based role requiring daily engagement in assay execution, experimental planning, sample and reagent preparation, instrument operation, data analysis, documentation, troubleshooting support, and technical communication. Ph.D. candidates are preferred, while M.S. and B.S. candidates with strong relevant industry experience will also be considered. Essential Functions: Perform hands-on laboratory work to support immunoassay development, optimization, platform evaluation, method transfer support, validation readiness, lifecycle management, and routine analytical testing. Engage daily in laboratory operations, including assay execution, reagent preparation, sample handling, study setup, instrument use, data review, documentation, laboratory organization, and coordination of testing priorities. Design and execute experiments under scientific guidance to support fit-for-purpose immunoassay development for potency, antigenicity, identity, impurity, characterization, comparability, release, and stability needs. Support evaluation of immunoassay platforms and formats, including ELISA, MSD, bead-based assays, multiplex assays, automation-enabled workflows, and other ligand-binding technologies. Support immunoassay troubleshooting studies by executing struct...