Senior Associate Scientist, In Vivo Pharmacology, Oncology
About PerceptiveOur mission is to shape the future of clinical research. With decades of experience and the brightest minds in the industry, we help the global biopharmaceutical industry bring new, advanced medical treatments to market, faster.We seek to change the world, and with the support of our teams across the globe, we flourish together. At Perceptive, we are one team. We learn, grow and win together. Are you ready to help change the world?Apart from job satisfaction, we can offer you:HEALTH: - Medical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA) and Health Savings Accounts (HSAs)YOURSELF:- Paid time off policy including holidays and sick time- Internal growth and development programs & trainingsWEALTH: 401(k) program, life & accident insurance and disability insuranceAbout the roleWe are seeking a motivated and skilled Senior Associate Scientist to support validation and execution of our imaging studies using preclinical in vivo oncology- models. This role is central to our preclinical research team and involves building CDx and clinically relevant PDx platforms and hands-on work applying these models with nuclear medicine (PET/SPECT) and computed tomography (CT), MRI, Bioluminescence Imaging. The successful candidate will also provide technical support across a range of in vivo studies including efficacy, biodistribution, pharmacokinetics, tolerability, and dosimetry and ex vivo analysis of target tissues of relevance in oncology, xenograft models.Key Responsibilities Essential Functions: Aid in the management of the Animal Care Facility (ACF) Ordering of animals and supplies Sanitization and equipment maintenance Follow, execute and write laboratory specific SOP’s related to role Assess study protocols for experimental details Participate in protocol reviews Lead projects and schedule necessary In-Vivo tasks Meet and determine timelines related to protocol execution Assess animal health conditions, communicate with Attending Veterinarian (AV) and provide necessary animal health care Learn technical/theoretical applications involved in executing pre-clinical studies Cell culture, inoculation, aseptic technique and contamination prevention Proficiency monitoring tumor volume, body weight, clinical signs and model- dependent humane endpoints Maintain clear and concise laboratory notes Perform data quality control and upload relevant documents upon study completion Work with IACUC to implement and ensure compliance of animal use protocols Preferred functioning set of classical skills: Test article administration IV, IP, SC, IM, PO Perfusion Compound handling Tissue resection Biological sampling procedures Execution of: Efficacy studies Biodistribution studies Pharmacokinetic studies&nbs...