Jade Biosciences

Senior Clinical Scientist

Boston; Remote; San Francisco; VancouverFull timeSenior$175,000 - $190,000 / yearPosted 15 days ago
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About Jade Biosciences  Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn. Role Overview  We are seeking a highly motivated and experienced Senior Clinical Scientist to support clinical development programs in nephrology, with a focus on rare or immune-mediated kidney diseases. This individual will play a key role in translating clinical strategy into high-quality execution of late-stage phase clinical trials. This is an exciting opportunity to join a growing biotechnology company where individual contributions have significant impact. The ideal candidate thrives in a fast-paced, collaborative environment, demonstrates strong scientific and operational expertise, and takes ownership of key deliverables. This newly created position will report to the Executive Medical Director of Clinical Development. The role is fully remote and will require periodic travel for investigator meetings, study team meetings, conferences, and other business activities.  Key Responsibilities  Clinical Development and Study Execution  Serve as the Clinical Scientist for one or more Phase 2 and/or Phase 3 clinical studies.   Contribute to study design, protocol development, and protocol amendments.   Develop and review study-related documents including:   Protocols  Investigator's Brochures  Informed Consent Forms  Clinical study reports  Study manuals and training materials  Safety management plans  Provide scientific oversight throughout study conduct to ensure protocol compliance and data quality.  Partner closely with Clinical Operations to support study start-up, enrollment, trial execution, and close-out activities.   Participate in investigator meetings, site training, and scientific discussions with investigators and key opinion leaders.    Data Review and Interpretation  Lead ongoing data review and medical monitoring activities in collaboration with Medical Monitors.  Identify clinical trends, protocol deviations, safety signals, and data quality issues.  Collaborate with Data Management and Biostatistics to develop:   Data review plans  Edit che...