Senior Director, Clinical Research-Medical Director (Oncology)

Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.  Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company. We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best. THE OPPORTUNITY The Senior Director, Clinical Research (Oncology) will serve as a Medical Director/Medical Monitor within Oncology Clinical Development, providing medical leadership for ongoing clinical trials and ensuring the safety of patients enrolled across Vir Bio’s oncology studies. This role will be responsible for medical monitoring activities, clinical decision making, safety oversight, protocol execution, investigator engagement, and cross-functional collaboration throughout the lifecycle of clinical trials. The successful candidate will be an experienced Oncology MD with deep expertise in clinical research, medical monitoring, and oncology drug development across early and late-stage studies. The role requires a physician leader with a strong track record of serving as a Medical Monitor and Clinical Research Physician, partnering closely with Clinical Operations, Clinical Scientists, Pharmacovigilance, Biometrics, and Regulatory teams to ensure safe, high-quality study execution. This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office. WHAT YOU'LL DO Serve as the lead Medical Monitor and Clinical Research Physician for one or more oncology clinical trials, providing ongoing medical oversight and patient-level clinical decision-making Review and interpret emerging safety and efficacy data, assess adverse events and safety signals, and partner with Pharmacovigilance to support benefit-risk assessments and patient safety Act as the primary medical contact for investigators and study sites, providing guidance on patient eligibility, safety management, protocol implementation, and complex clinical questions Lead medical monitoring activities across Phase 1-3 studies, ensuring high-quality study conduct, data integrity, protocol compliance, and regulatory readiness Contribute to the development of study protocols, amendments, informed consent forms, safety management plans, clinical study reports, and clinical sections of regulatory submissions Partner closely with Clinical Operations, Cl...