Senior Lab Systems Scientist

Location: On-Site in Boulder, CO (Foresight Dx business unit, a Natera company) Foresight Diagnostics is a molecular diagnostics company pioneering non-invasive cancer detection through highly sensitive, cell-free DNA-based liquid biopsy technologies. Our proprietary methods - originally developed at Stanford University - are designed to detect smaller tumors earlier and enable more personalized treatment strategies for patients with cancer.  We sit at the intersection of molecular biology, bioinformatics, and next-generation sequencing (NGS), and we translate rigorous science into clinically meaningful solutions. Following our acquisition by Natera, we now combine the agility of a mission-driven startup with the scale and resources of a global leader in cell-free DNA testing. It’s an exciting moment to join us.  Headquartered in Boulder, Colorado, our team operates in a high accountability, collaborative environment where quality and continuous improvement aren’t just values - they’re how we work every day. About The Role The Senior Laboratory Systems Scientist at Foresight Diagnostics is a critical senior individual contributor within our Operational Excellence and Process Engineering team and is responsible for leading the architecture, development, and continuous improvement of laboratory systems that enable scalable clinical testing operations. This role serves as a scientific and technical leader responsible for designing, implementing, and optimizing laboratory technologies leveraging advanced scientific and operational judgement to translate complex operational needs into robust, scalable laboratory systems that meet regulatory, safety and business requirements.  The Senior Laboratory Systems Scientist will collaborate with R&D, Software, Bioinformatics, Laboratory Operations, Automation Engineering, and RA/QA to lead cross-functional initiatives including technology transfer, system development, validation strategy, and operational process optimization. This is a full-time position based in Colorado working standard business hours; however, the role will require flexibility to work diverse schedules, including evenings and weekends, and holidays for critical deliverables. This position will report directly to the Senior Manager, Operational Excellence and Process Engineering.  What you will do Independently assess assay and operational processes to identify gaps and risk signals through the interpretation of complex performance and analytical data and operator feedback. Through proper problem definition and cross-functional stakeholder alignment, build business cases to present to senior leadership detailing scope, requirements, timeline, resourcing, and a project plan. Design, develop, and implement and/or tech transfer programs and robust, scalable processes that enable laboratory operations to meet regulatory, safety and business requirements.  Under the guidance of the Laboratory Director and Senior Di...