Sr. Research Associate, Clinical Biomarker Laboratory, Flow Cytometry

The Role:Moderna is seeking a talented and motivated Senior Research Associate to join the Clinical Flow Cytometry group to serve as a technical expert for the generation of high parameter flow cytometry data under GCLP guidelines to support clinical programs across multiple therapeutic areas.  The Senior Research Associate will work with a team of scientists to return high quality data for clinical trials conducted by Moderna.  This will include development of cell-based flow cytometry assays, performing fit-for-purpose validations, and executing clinical sample testing.  You will be an integral part in applying high parameter flow and complex assays to generate key clinical data to drive clinical trial decisions. Here's What You’ll Do: Execute clinical sample testing under GCLP guidelinesConduct ex vivo stimulation for functional profiling of immune responses using intracellular cytokine staining on clinical trial PBMC samplesHigh parameter immunophenotyping on PBMCs, whole blood samples, and tissue samplesPBMC isolation and cryopreservation from blood productsStrict adherence to protocols related to technical details and documentation to ensure assay rigor and repeatabilityDeliver high quality data within defined timelines and aligned to current industry expectations  Play a prominent role in a team developing high parameter spectral flow cytometry assays and applying them to clinical trial samples to generate key data.  Adhere to established experimental workflows and documentation procedures while working to improve processes for accuracy and efficiencyRun experiments independently from sample prep to acquisition, and accurately analyze (FCSExpress) and present dataUnder the direction of the Study Lead, participate in assay development and validation studiesWork with the team to identify, test feasibility, and implement emerging laboratory techniquesAssist in general lab organization and other shared dutiesMaintain and support safe lab practices and environmentThis position is site-based, requiring you to be at Moderna’s site full-time. This position is not eligible for remote workOccasionally the job may require overtime work or weekend shift as neededHere’s What You’ll Bring to the Table:BS or MS in Immunology, Life Sciences, Biology, or related field; 3+ years lab experienceDirect flow cytometry experience from sample processing and staining, through sample acquisitionExperience in a regulated lab is desiredExperience with cell culture, ex vivo assays, and cell isolation from tissuesExperience in assessing cell-mediated immunity through flow cytometry: ex vivo stimulation of PBMC and intracellular cytokine staining for functional profiling is desiredPossess good computational skills, experienced with Word, Excel, Power Point, and GraphPad PrismDemonstrated level of independence An effective communicator and collaborator in a project team with good written and presentation skills Flexibility ...