Vice President / Senior Vice President, Clinical Development Lead – Immunology & Program Leadership

Position Summary  What if... We could harness the power of Flagship’s scientific platforms and create novel treatment options that benefit more patients, sooner?   Pioneering Medicines, an initiative of Flagship Pioneering, is building a world-class biopharmaceutical R&D capability focused on conceiving and developing life-changing treatments for patients by harnessing the power of Flagship's scientific platforms and applying those innovative approaches to serious diseases with unmet medical need. Unique to Pioneering Medicines’ approach is the opportunity to combine platforms to create truly novel and potentially transformative treatments.   We are seeking a highly accomplished VP/SVP, Clinical Development Program Leader with deep expertise in Immunology and demonstrated Program Leadership experience to drive the strategy, execution, and cross-functional advancement of multiple innovative therapeutic programs entering the clinic. This role reports to the Chief Medical Officer of Pioneering Medicines This individual will partner closely with platform companies, Flagship leadership, and external stakeholders to advance programs from early translational stages through IND and early clinical development.  This role is distinct in its portfolio-wide impact and platform-integrated model, requiring a leader who can operate across multiple programs, and modalities. This individual will serve as both the clinical leader and a key program enterprise leader, responsible for integrating scientific, clinical, operational, regulatory, and portfolio considerations to drive successful development of immunology assets from early clinical development through human proof of concept and beyond.  The ideal candidate is a seasoned physician-scientist with deep translational medicine expertise and an enterprise leader with a strong track record of advancing complex immunology programs, leading cross-functional teams, influencing organizational strategy, and operating effectively in a dynamic biotechnology environment.  Key Responsibilities  Clinical Development Leadership  Lead the overall clinical development strategy for multiple immunology programs across early development.   Design and oversee integrated clinical development plans aligned with scientific rationale, patient needs, competitive positioning, and corporate objectives.   Provide clinical leadership for Phase I and II studies, including protocol design, dose selection, endpoint strategy, and data interpretation.   Ensure clinical programs are executed with scientific rigor, operational excellence, and regulatory compliance.   Drive indication prioritizat...