Manager/Sr. Manager, Patient Supply Operations

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.   Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.Legend Biotech is seeking a Manager/Sr. Manager, Patient Supply Operations as part of the Patient Supply Strategy & Operations team based in Somerset, NJ.   Role Overview Legend Biotech is seeking an experienced and driven Manager/Sr. Manager- Patient Supply Operations to join our Technical Development team. This role will report to the Director of Patient Supply Strategy & Operations and be responsible for supporting hands on execution of global patient supply activities for early clinical Cell and Gene Therapy programs (Allogenic and In-Vivo). This role is accountable for operational readiness of investigational product supply from IND through First-In-Human and early Phase studies, in alignment with regulatory requirements. The successful candidate will translate clinical and CMC needs into executable supply plans, ensure compliant distribution, inventory control, and QP release, and partner cross functionally to enable uninterrupted delivery of product to global clinical sites. This is a hands-on role requiring strong ownership of execution, vendor oversight, accountability, independent issue resolution in a fast-moving early phase environment. Key Challenges Building global supply chain infrastructure in an early-phase, rapidly evolving environment. Executing first-time country start-ups, particularly in ex-US regions with regulatory requirements. Managing import/export processes and IOR/EOR models across multiple countries. Ensuring reliable delivery of temperature-sensitive products (LN2, -80°C). Responding to real-time logistics issues while maintaining compliance and timelines. Key Deliverables Execution of FIH and early-phase global clinical shipments. Establish global depot and logistics network, including ex-US infrastructure. Define and implement import/export workflows and IOR/EOR models. Execute per country-specific clinical supply playbooks and SOPs. Operational cold-chain distribution lanes with defined performance metrics.   Key Responsibilities Supply Pl...