Senior Clinical Trial Manager, Patient Support Operations

About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As the Senior Manager, Patient Support Operations, you will report to the Head of Clinical Operations to serve as the primary "Patient and Site Navigator" for our Type 1 Diabetes (T1D) program. You will lead the operational orchestration of drug product movement once received at the clinical site. Your primary focus will be managing the chain of custody responsibilities from a clinical operations perspective, ensuring seamless logistics and receipt at the site, while providing expert support for successful surgical outcomes for our patients. Additionally, you will be an integral part of the Clinical Development Operations team supporting the planning, execution, and management of clinical trials in accordance with regulatory requirements and industry best practices for Sana programs. This is a builder-operator role: you will translate strategy into execution by standing up workflows, pressure-testing processes, and ensuring systems, teams, and partners are aligned and ready to deliver reliably at the clinical site level. What you’ll do Own and manage the clinical operational chain of custody for drug products, with accountability for clinical trial sites, including clinical site logistics, documentation, and receipt protocols. Partner closely with Technical Operations and Clinical Development stakeholders to refine and finalize the hand-off procedures between manufacturing and clinical operations. Serve as the primary, site-facing, single point of contact accountable for ensuring sites are fully equipped and prepared for receipt, handling, and surgical implantation of cellular medicines; proactively identify gaps and drive closure. Collaborate with surgical and transplant teams in hospital settings to provide real-time operational support and technical guidance during dosing/transplant; lead issue triage and escalate time-critical risks to Clinical Operations leadership as needed. Coordinate between Technical Operations and clinical providers to ensure execution aligns to program timelines and quality standards; track milestones, surface risks early, and drive timely resolution with clear owners. Onboard and manage clinical sites, owning readiness assessments and capability evaluations for complex cell therapy procedures; monitor ongoing operational performance and implement corrective actions in partnership with stakeholders. Develop, maintain, and continuously improve specialized playbooks for site-level patient operations and surgical logistics, ensuring controlled documentation and consistent implementation across sites. Responsible for both remote and on-site monitoring, training, documentation, and coordination of site teams, schedules and operational details. Oversee clinical trial ...